conjunction
nonetheless; nevertheless; but; yet
Conjunction used to introduce a statement that contrasts with or is surprising given what was just said. Similar to それなのに but slightly more formal or written.
雨が降っていた。それにもかかわらず、彼は出かけた。
It was raining. Nonetheless, he went out.
彼は若い。それにもかかわらず、とても落ち着いている。
He is young. Nevertheless, he is very composed.