大たい切せつに

adverb

carefully; with great care; with caution

Used when handling something with care, treating something as precious, or acting cautiously to avoid damage or mistakes.

• この花か瓶びんは大たい切せつに扱あつかってください。

  Please handle this vase with care.

• 祖そ母ぼからもらった手て紙がみを大たい切せつにしまってある。

  I keep the letter from my grandmother carefully stored away.