i-adjective
hard to handle; difficult to deal with; unwieldy
Describes something that is physically awkward to manipulate or a person/situation that is troublesome to manage.
この荷物は大きくて扱いにくい。
This luggage is big and hard to handle.
彼は気分屋で扱いにくい人だ。
He is moody and difficult to deal with.
Antonym; means easy to handle or manage.
More casual and subjective; focuses on the speaker's feeling of bother, while 扱いにくい is more objective about difficulty of handling.
Compound of 扱い (noun form of 扱う, 'to handle') + にくい ('difficult to do').