抜ぬけ目めがないConjugationMeanings1expression, i-adjectiveshrewd; astute; cunning; alertDescribes a person who is sharp, misses no opportunity, and is always on the lookout for their own advantage. Can be positive (astute) or negative (calculating) depending on context.See also: 抜け目ない · 抜け目のない彼かれは抜ぬけ目めがないから、契けい約やく書しょの細こまかい