A person who leads, guides, or instructs others in an organization, activity, or field. Can refer to a political leader, team coach, spiritual guide, or mentor.
As a mentor to young employees, I give advice every day.
先生
先生 is a teacher or instructor, typically in an academic or professional setting. 指導者 is broader and can refer to anyone who provides guidance, not necessarily in a classroom.
Etymology
Compound of 指導 (shidō, 'guidance') and 者 (sha, 'person').