noun
torture; pains of hell
Refers to physical or mental torment, often with a literary or religious connotation of hellish suffering.
地獄の責め苦を想像すると怖くなる。
Imagining the tortures of hell is frightening.
彼は良心の責め苦に耐えられなかった。
He couldn't bear the torment of his conscience.
Compound of 責め (blame, torture) and 苦 (pain, suffering). The exact historical derivation is uncertain, but the combination naturally conveys the idea of torment.